Thursday, December 14, 2017

Insilico Medicine to Keynote at the A4M Las Vegas alongside Peter Diamandis and Valter Longo (IMAGE)

Wednesday, 13th of December, 2017, Baltimore, MD - Insilico Medicine, a Baltimore-based company specializing in the application of artificial intelligence for drug discovery, biomarker development and aging research, is pleased to announce the lecture of its founder and CEO, Dr. Alex Zhavoronkov, at 25th Annual World Congress, 14-16 Dec 2017, organized by American Academy of Anti-Aging Medicine (A4M).
Dr. Zhavoronkov's session will focus on the latest advances in artificial intelligence for development and tracking of anti-aging interventions. The lecture will cover the novel approach of developing evidence-based nutraceuticals via in silico prediction, in vitro and in vivo validation and post-marketing analysis using Young.AI project. Young.AI, currently in the beta-test version is an online service for tracking the biological age using the deep-learned photographic and basic blood biochemistry-based predictors.
"It is a privilege to speak alongside Peter Diamandis, Valter Longo, Michael Weiner and the others at the 25th annual A4M event. Insilico Medicine aspires to be the leader in artificial intelligence for longevity biotechnology and one of the many areas we are working on our evidenced-based nutraceuticals. Millions of people are consuming a broad range of nutraceuticals on a daily basis and do not track their progress. By introducing a range of nutraceuticals identified using AI and a pilot system to track their progress - Young.AI, we are trying to develop a novel drug discovery cycle that may substantially reduce the failure rates and the discovery and development time in the pharmaceutical industry", said Alex Zhavoronkov, PhD, the founder and CEO of Insilico Medicine, Inc.
"Issues following the development of novel molecules into medicines are undeniable, especially in the field of aging. Safe nutraceuticals offer one of a few ways to speed up the translation of anti-aging interventions into humans. With recent developments in the field of actionable biomarkers of biological age these interventions can be quickly evaluated by Young.AI platform", commented Alex Aliper, President of EMEA, Insilico Medicine, Inc.
Insilico Medicine was the first company to apply deep generative adversarial networks (GANs) to the generation of new molecular structures with specified parameters and published seminal papers in Oncotarget and Molecular Pharmaceutics. Another paper published in Molecular Pharmaceutics in 2016 and demonstrated the proof of concept of the application of deep neural networks for predicting the therapeutic class of the molecule using the transcriptional response data, received the American Chemical Society Editors' Choice Award. One of the recent papers published in November 2017 described the application of the next-generation AI and blockchain technologies to return the control over personal data back to the individual. 
"In the age of personal and healthcare data, it's highly important to track, understand and control your data. With Young.AI beta everyone can take advantage of the recent advances in deep learning technology to track the aging process at every level and evaluate the importance of different biomarkers. In order to better understand the effectiveness of the lifestyle as well as supplement and drug intake, Young.AI system incorporates various types of interventions and metadata", said Alexander Zhebrak, the director of product development and CTO of Insilico Medicine, Inc.
The 25th Annual World Congress in Las Vegas marks a quarter of a century since A4M began its original mission: to build awareness and deliver innovative, cutting-edge scientific education focused on longevity, and prolonging the human lifespan. The audience of the congress spans the globe, and its invited speakers, keynotes, and faculty panels assist attendees in implementing and integrating new therapies into practice.
###
For further information, images or interviews, please contact:
Contact: Qingsong Zhu, PhD 
zhu@pharma.ai 
Website: http://www.Insilico.com
About Insilico Medicine, Inc
Insilico Medicine, Inc. is an artificial intelligence company headquartered at the Emerging Technology Centers at the Johns Hopkins University Eastern campus in Baltimore, with R&D and management resources in Belgium, Russia, UK, Taiwan and Korea sourced through hackathons and competitions. 
The company utilizes advances in genomics, big data analysis, and deep learning for in silico drug discovery and drug repurposing for aging and age-related diseases. Insilico pioneered the applications of the generative adversarial networks (GANs) and reinforcement learning for generation of novel molecular structures for the diseases with a known target and with no known targets. In addition to working collaborations with the large pharmaceutical companies, the company is pursuing internal drug discovery programs in cancer, dermatological diseases, fibrosis, Parkinson's Disease, Alzheimer's Disease, ALS, diabetes, sarcopenia, and aging. Through a partnership with LifeExtension.com the company launched a range of nutraceutical products compounded using the advanced bioinformatics techniques and deep learning approaches. It also provides a range of consumer-facing applications including Young.AI and Aging.AI and operates Chemistry.AI intended to capture the tacit knowledge of medicinal chemists. 
Through a partnership with the BitFury Group, the company is working on a range of AI solutions for blockchain to help return the power over life data back to the individual. The company raised venture capital and partnered with Juvenescence Limited, a holding company focused on longevity biotechnology. The company aspires to become the "Bell Labs" for artificial intelligence and associated technologies for healthcare and longevity biotechnology and commercialize its research by forming subsidiaries around the specific technologies and licensing the intellectual property, molecules and data to the biotechnology and pharmaceutical companies. In 2017, NVIDIA selected Insilico Medicine as one of the Top 5 AI companies in its potential for social impact. Brief company video: https://www.youtube.com/watch?v=l62jlwgL3v8

Tuesday, December 12, 2017

Insilico Medicine Named to the Global Top 100 AI Companies by CB Insights

CB Insights today named Insilico Medicine to the prestigious AI 100, a select group of promising private companies working on groundbreaking artificial intelligence technology. CB Insights CEO and co-founder Anand Sanwal will reveal the full list of the second annual AI 100 companies at the A-ha! conference in San Francisco.
"Last year's AI 100 enjoyed amazing success in the year since earning this recognition. 55 of them went onto raise additional funding nearing $2B and 5 were acquired. This year's list was culled from 1000+ applications and looks even more impressive. These are companies using artificial intelligence in industries from drug discovery and cybersecurity to robotics and legal tech. I'm happy that CB Insights is able to shine a light on the founders and companies that will revolutionize these industries and look forward to seeing what they do in 2018 and beyond." said CB Insights CEO Anand Sanwal.
The CB Insights research team selected the AI 100 companies based on criteria, examining company-submitted data and the company’s Mosaic Score. The Mosaic Score, based on CB Insights’ National Science Foundation-funded algorithm, measures the overall health and growth potential of private companies. Through this evidence-based, statistically-driven approach, the Mosaic Score can help predict a company’s momentum, market health and financial viability. 
“In 2014 Insilico Medicine made a bet on the deep learning technology and since then established over 250 industry and academic collaborations in both drug discovery and biomarker development and we became an innovation driver for the pharmaceutical industry. We are very happy to be recognized as one of the top 100 global AI companies by CB Insights, one of the top industry analysts,” said Alex Zhavoronkov, PhD, the CEO of Insilico Medicine, Inc
In May 2017 Insilico Medicine was named top 5 AI companies for social impact by Nvidia. It pioneered the application of the generative adversarial networks (GANs) and reinforcement learning to generation of new molecular structures with the specific set of characteristics. It also pioneered using age as the main feature for multi-modal multi-omics data integration, biomarker development, target identification and transfer learning. 
“In 2014 we just got our signaling pathway perturbation analysis algorithms to work very well after several years of hard work and got venture capital to develop them further. We even got some freedom and the tools to focus on our primary interest - aging research. So the idea of refocusing the company into deep learning, which was very new back then was met with some internal resistance. But nowadays we probably have one of the most efficient and productive DL teams in the world. We are hiring through hackathons and competitions in the many countries, where the DL talent is not overpriced and bridge the gap between the DL scientists, biologists and medicinal chemists very quickly. We also perform literature reviews at least twice a week to ensure that we incorporate all of the latest advances in DL into our models. We are happy to see that this hard work is recognized by CB Insights.” said Alex Aliper, president of Europe, Insilico Medicine, Inc.
Insilico Medicine was the first company to apply deep generative adversarial networks (GANs) to the generation of new molecular structures with specified parameters and published seminal papers in Oncotarget and Molecular Pharmaceutics. Another paper published in Molecular Pharmaceutics in 2016 and demonstrated the proof of concept of the application of deep neural networks for predicting the therapeutic class of the molecule using the transcriptional response data, received the American Chemical Society Editors' Choice Award. One of the recent papers published in November 2017 described the application of the next-generation AI and blockchain technologies to return the control over personal data back to the individual. 
About CB Insights
Our team builds technology that helps corporations guess less and win more. We aggregate and analyze terabytes of data and use machine learning, algorithms and data visualization to help corporations replace the three Gs (Google searches, gut instinct and guys with MBAs) so they can answer massive strategic questions using probability not punditry.
Contact:
Farrah Kim, Senior Public Relations & Communications Manager
fkim(at)cbinsights.com
212-292-3148
For more information about the AI 100, visit:
https://www.cbinsights.com/research-ai-100
About Insilico Medicine, Inc
Insilico Medicine, Inc. is an artificial intelligence company located at the Emerging Technology Centers at the Johns Hopkins University Eastern campus in Baltimore, with R&D resources in Belgium, Russia, and the UK sourced through hackathons and competitions.
The company utilizes advances in genomics, big-data analysis, and deep learning for in silico drug discovery and drug repurposing for aging and age-related diseases. The company is pursuing internal drug discovery programs in cancer, Parkinson's Disease, Alzheimer's Disease, ALS, diabetes, sarcopenia, and aging.
Through its Pharma.AI division, Insilico provides advanced machine learning services to biotechnology, pharmaceutical, and skin care companies, foundations and national governments globally. In 2017, NVIDIA selected Insilico Medicine as one of the Top 5 AI companies in its potential for social impact. http://www.insilico.com

Contact:
Qingsong Zhu, PhD
zhu(at)pharma.ai