Tuesday, March 17, 2020

北京泰德制药与英矽智能签署AI辅助抗癌药开发计划案,启动战略联盟合作



中国北京和香港-2020年3月17日, 中国生物制药有限公司旗下的北京泰德制药股份有限公司(北京泰德)携手创新人工智能公司Insilico Medicine (英矽智能)共同签署「AI辅助抗癌药开发计划案」,启动战略联盟合作。合作款项包括首付款,里程碑款项和销售上市绩效奖励。北京泰德扮演领头羊的角色,已掌握潜在靶点可望应用于治疗多种类型的癌症;英矽智能将建构全新深度学习模型,针对此潜在靶点设计小分子抗癌新药,这将是史上首度利用AI发现造福多种类型癌症患者的新药。
中国生物制药有限公司谢其润主席表示”这是正大制药集团旗下药企二度与英矽智能展开合作,我们预见AI技术应用于药物发现和医疗保健领域巨大的发展潜力,因此将会在AI辅助药物开发方面投入更多资金”。
英矽智能的首席执行长亞歷克斯扎沃洛科夫 (Alex Zhavoronkov)博士对于双方的合作也感到相当振奋,同时表示:我们的合作朝向共同目标前进,协力寻找治愈癌症的方式,透过双方的优势与资源整合,相信战胜癌症指日可待。
北京泰德是中国一家能够研发、生产、销售一系列靶向药物的高科技制药企业,始终秉持「质量第一,患者至上」的信念,并且持续创新,敢于挑战其他制药业难以开发的产品,在英矽智能的创新人工智能平台辅助下,双方将一同进入药物研发的全新时代。本次合作堪称完美的结合,北京泰德与英矽智能皆期待藉由本次的战略联盟合作以开启长久的伙伴关系,共创双赢共荣局面。
去年九月,英矽智能在自然生物科技期刊(Nature Biotechnology)发表具有代表性的论文,从确定靶点到通过初步生物学验证,利用生成性張力強化學習模型GENTRL(Generative Tensorial Reinforcement Learning)只用了46天的时间,即能找出具有潜力的激酶抑制剂分子。创新的AI技术有助于加速药物发现过程,北京泰德即将一同见证这制药革新的时代。
关于北京泰德制药股份有限公司(北京泰德):
北京泰德药业有限公司是一家集研发、生产、销售为一体的创新型医药企业。北京泰德是中国生物制药有限公司的主要子公司,专注于在心血管、疼痛管理、呼吸和肿瘤领域开发创新和特殊制剂药物。目前拥有在不同阶段的化学创新药物和生物创新药物。其中针对各种纤维化疾病的完全创新小分子正在美国展开临床一期试验,同时,有多个美国仿制药已经获批或正在上市申请。公司专注于国内市场,同时瞄准世界市场,并坚持“关怀生命,精益创新”为宗旨。勤奋耕耘,矢志不移,探索行业健康发展之路,成为一个利国家、利企业、利员工的和谐企业。
关于Insilico Medicine(英矽智能):
Insilico Medicine(英矽智能)是一家新兴人工智能公司,总部位于香港,并且在全球六个国家设有办公室。该公司致力于通过开发和应用下一代深度学习方法来改变制药行业,以实现药物发现和药物开发的效率和成功率提升。英矽智能持续与最具创新性的生物制药公司合作,开展与疾病相关的分析,以验证其解决方案并生成高质量的机器可学习的数据。
自2015年以来,英矽智能在全球率先运用神经对抗网络(GAN)和强化学习(RL)来开发新的药物分子,这项技术可同时运用于已知靶点的药物设计和未知靶点的发现。去年9月该公司在自然生物科技期刊Nature Biotechnology 发表从靶点到候选分子仅需3周的实验结果,广受好评, 并于日前完成了3700万美元的B轮融资。
联系人:ai@insilico.com
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Insilico Medicine to present at the Systems Aging Gordon Research Conference

New deep biomarkers of aging to be presented at the Systems Aging Gordon Research Conference

March 13, 2020 - Insilico Medicine will present its latest results in modern and next-generation AI for drug discovery and productive longevity at the Systems Aging Gordon Research Conference, in Mount Snow, Vermont, June 2020.
Aging is a complex process that has been observed in all biological systems at every level of organisation. Some anti-aging interventions have demonstrated life-extending effects in model organisms. Although very good progress has been made in the area, the translation of these interventions in human clinical practice remains limited due to the absence of comprehensive ageing biomarkers. Recent studies suggest that a set of biomarkers, rather than any individual biomarker, constitute the most effective means of assessing the health status. The presentation will cover the development of comprehensive biomarkers of aging using deep learning and blood biochemistry, transcriptomics, and imaging data.
"I am happy to present our latest research at the Systems Aging Gordon Research Conference 2020. The topic of Biomarkers of Aging is rapidly gaining popularity, and we are happy to be at the leading edge of research and one of the innovation drivers in the area." said Alex Zhavoronkov, Ph.D., Founder, and CEO of Insilico Medicine.
"Alex Zhavoronkov is a clear leader in applying AI approaches to diverse aging-related problems. We look forward to learning about the new advances he has made. This integrative approach is critical for further development of the field," said Vadim Gladyshev, Ph.D., Professor of Medicine at Brigham and Women's Hospital, Harvard Medical School, and chair of the Systems Aging conference.
The inaugural Systems Aging Gordon Research Conference will be held at Mount Snow (West Dover, Vermont, USA) on May 31 - June 5, 2020. The conference program is set around the theme of "Systemic Processes, Omics Approaches and Biomarkers in Aging". The program will include speakers from diverse fields who are united in their pursuit of pioneering aging research. The 2020 Systems Biology GRC will set the stage for subsequent meetings and future development of this field, with the idea to ultimately help delay and reverse aging and age-related pathology.
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For further information, images or interviews, please contact:
Contact: Klug Gehilfe ai@pharma.ai
About Insilico Medicine
Insilico Medicine is an artificial intelligence company with offices in six countries and regions striving to accelerate three areas of drug discovery and development: disease target identification, generation of novel molecules (generative chemistry) and synthetic biological data (generative biology), and prediction of clinical trial outcomes. The Company was the first to apply the generative adversarial networks (GANs) and reinforcement learning (RL) to generate new molecular structures with the specified parameters in 2015. In addition to collaborating with large pharmaceutical companies, Insilico Medicine is also pursuing internal drug discovery programs in different disease areas. 


Tuesday, March 10, 2020

FierceMedTech names Insilico Medicine as one of its 'Fierce 15' companies of 2019

9th of March, 2020, 9:00 AM ET --Insilico Medicine today announced that it has been named by FierceMedTech as one of 2019's class of Fierce 15, designating it as one of the most promising private medtech companies in the industry.
"Fierce is one of the two serious industry analytical powerhouses I get to read every day. So I need to congratulate my team for their heroic efforts and excellence in both AI and drug discovery on being included in this prestigious list. For five years we made bets on disruptive technologies with very limited resources and often struggled. But 2019 was a pivotal year for us as our end-to-end AI allowed us to come up with a pre-clinical asset portfolio that can rival successful biotechs, we got the best investors, and some of the smartest big pharma CEOs started looking at us as a promising biotech company," said Alex Zhavoronkov, PhD, co-founder, and CEO of Insilico Medicine.
The Fierce 15 celebrates the spirit of being "fierce"--championing innovation and creativity, even in the face of intense competition. This is FierceMedTech's 8th annual Fierce 15 selection.
"One of the true joys of covering this field is being able to talk with the people driving the next great medical advancements--technologies that may not just change a patient or parent's life, but also the day-to-day work of clinicians, surgeons, researchers and developers themselves," said Conor Hale, associate editor of FierceMedTech. "Potential breakthroughs such as these can ripple into new therapies, procedures and interventions, and ultimately more ways to heal more people."
An internationally recognized daily report reaching a network of over 90,000 medtech industry professionals, FierceMedTech provides subscribers with an authoritative analysis of the day's top stories. Every year FierceMedTech evaluates hundreds of private companies from around the world for its annual Fierce 15 list, which is based on a variety of factors such as the strength of its technology, partnerships, venture backers and competitive market position.
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About Insilico Medicine
Insilico Medicine is an artificial intelligence company with offices in six countries and regions striving to accelerate three areas of drug discovery and development: disease target identification, generation of novel molecules (generative chemistry) and synthetic biological data (generative biology), and prediction of clinical trial outcomes. The Company was the first to apply the generative adversarial networks (GANs) and reinforcement learning (RL) to generate new molecular structures with the specified parameters in 2015. In addition to collaborating with large pharmaceutical companies, Insilico Medicine is also pursuing internal drug discovery programs in different disease areas. Website: http://insilico.com/
About FierceMedTech
FierceMedTech keeps biopharma executives, device developers, engineers, and researchers updated on the must-know news, trends and developments in medical technology. More than 90,000 top industry professionals rely on FierceMedTech for an insider briefing on the day's top stories.
About Questex
Questex helps people live better and longer. Questex brings people together in the markets that help people live better: travel, hospitality and wellness; the industries that help people live longer: life science and healthcare; and the technologies that enable and fuel these new experiences. We live in the experience economy--connecting our ecosystem through live events, surrounded by data insights and digital communities. We deliver experience and real results. It happens here.
FierceMedTech PR Contact:
Rebecca Willumson 
Questex, FierceMedTech 
202-824-5050 
rwillumson@questex.com
Insilico PR Contact:

Klug Gehilfe 
ai@insilico.com