Deep Longevity Inc to collaborate with and launch aging clocks with Human Longevity Inc

Deep Longevity Inc to collaborate with and provide an extensive range of deep biomarkers of aging to Human Longevity Inc

Tuesday, 14th of July, 2020, San Diego, CA (9:00AM) -- Today, Deep Longevity Inc, a developer of deep biomarkers of human aging, and Human Longevity Inc announce a collaboration to deploy an extensive range of AI-powered aging clocks. Deep Longevity is to develop and provide the customized predictors of human biological age to the network of Human Longevity Inc concierge longevity clinicians. 

Deep Longevity is a longevity-focused artificial intelligence spin-off from Insilico Medicine, Inc, one of the global leaders in deep learning for drug discovery and biomarker development. Deep Longevity exclusively licensed a portfolio of granted and pending patents on aging clocks developed using the latest advances in artificial intelligence. 

Deep Longevity aging clocks are supported by a number of academic publications covering summarized in a recent review titled "Biohorology and biomarkers of aging: Current state-of-the-art, challenges and opportunities."

Human Longevity Inc recently published a research paper on a large cohort of healthy patients in the journal Proceedings of the National Academy of Sciences (PNAS) titled "Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imaging." Deep Longevity and Human Longevity will engage in research to validate the deep aging clocks on this cohort. 

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About Deep Longevity, Inc

Deep Longevity is a global leader in deep learning for aging research specializing in the development of deep biomarkers of aging using clinical blood tests, transcriptomic, proteomic, epigenetic, microbiome, behavioral, wearable, imaging, and multiple other data types. The company holds exclusive licenses to a comprehensive IP portfolio including both granted and pending patents. The company provides a broad range of deep aging clocks to some of the world's most advanced longevity clinics and physicians and is developing a range of simple consumer applications to track the rate of aging at the individual level. The company is developing a comprehensive decision support system for physicians to enable the development of personalized longevity protocols utilizing the latest advances in longevity biotechnology. Website: http://www.DeepLongevity.com

About Human Longevity, Inc.

Human Longevity, Inc. is a genomics-based, health intelligence company empowering proactive healthcare and enabling a life better lived. HLI's business focus includes the Health Nucleus, a genomic-powered, precision medicine center which uses whole-genome sequencing analysis, advanced imaging, and blood analytics, to deliver the most complete picture of individual health. For more information, visit http://www.humanlongevity.com.

About Health Nucleus

Health Nucleus clinics combine leading edge science with physicians who are experts in large data sets to interpret patients' data and guide them toward longer, healthier lives. Headquartered in San Diego, CA, Health Nucleus is revolutionizing precision health care with proprietary programs like 100+, a suite of annual tests, services and care that help preempt disease before symptoms arise. Health Nucleus uses whole genome sequencing analysis and advanced digital imaging along with personal biomarkers to deliver a complete picture of individual health. By harnessing 150 gigabytes of health data on each patient, Health Nucleus are able to pinpoint pre-symptomatic risks of cardiovascular disease, cancer, neurological disease and degradation, metabolic health status, and more. Health Nucleus is a subsidiary of Human Longevity, LLC

Insilico Medicine and Arctoris to collaborate on COVID-19 by combining robotics and AI

Insilico Medicine and Arctoris announced a technology partnership to jointly discover and profile new therapeutics against COVID-19 by combining robotics and AI

Thursday, 9th of July - Insilico Medicine, a biotechnology company developing an end-to-end drug discovery pipeline utilizing next-generation artificial intelligence, today announced a technology partnership with Arctoris, the world's first fully automated drug discovery platform, offering remotely accessible, pre-optimised and fully validated R&D processes for its partners and clients globally. The partnership enables the two companies to combine their unique strengths in AI-guided drug discovery for target identification and generative chemistry on the one hand, and robotics for rapid generation of high-quality cell-based, molecular and biochemical data on the other. The partnership propels the two companies' abilities to discover and validate novel molecules faster.

Contributing their strengths to the fight against COVID-19, the two companies utilized their unique state-of-the-art techniques to discover, synthesize, and profile a set of inhibitors for COVID-19 treatment. Insilico identified novel small molecules using its AI capabilities, with Arctoris rapidly evaluating the intended biological actions on its robotic platform. In a develop-test-refine loop, the partners iterated new molecules several times faster than the industry standard, providing unprecedented prospects for new drug discovery successes. The JAK inhibitor study profiled a set of potent inhibitors that can help patients by modulating the life-threatening cytokine storm caused by COVID-19.

"We are excited to announce our technology partnership with Insilico Medicine, a world-leader in AI-based drug discovery. We see tremendous value in combining our next-generation robotic platform with Insilico's unique capabilities in drug design. During the COVID-19 pandemic, time is of the essence, and this project demonstrates that together, we are able to accelerate the drug discovery process, and create and progress new drug candidates faster and cheaper," said Martin-Immanuel Bittner MD DPhil, Co-Founder & CEO of Arctoris.

"Arctoris developed an advanced robotics platform that can be used for a very broad spectrum of applications in drug discovery and biological data generation. We are very happy to partner with this Oxford-based company on our COVID-19 program. We discussed the collaboration for quite some time but this pandemic really highlighted the benefits of a close AI- and robotics- powered discovery integration," said Alex Zhavoronkov, PhD, founder, and CEO of Insilico Medicine.

Insilico and Arctoris have already been working together on BioTarget, a collaborative effort supported by Cancer Research UK to find new molecules for cancer treatment from partners globally, crowdsourcing the drug discovery process and making leading experimental tools accessible to researchers worldwide, thereby democratising the drug discovery ecosystem.

Further collaboration will focus on joint drug discovery projects in oncology, a field of particular interest to both Arctoris and Insilico, with their mission to eliminate age-related disease and promote healthy longevity.

For further information, images or interviews, please contact: ai@insilico.com.

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About Insilico Medicine

Since 2014 Insilico Medicine is focusing on generative models, reinforcement learning (RL), and other modern machine learning techniques for the generation of new molecular structures with the specified parameters, generation of synthetic biological data, target identification, and prediction of clinical trials outcomes. Recently, Insilico Medicine secured $37 million in series B funding. Since its inception, Insilico Medicine raised over $52 million, published over 80 peer-reviewed papers, applied for over 25 patents, and received multiple industry awards. Website http://insilico.com/.

For further information, images or interviews, please contact: Sian Marshall, Head of Office, media@arctoris.com

About Arctoris

Arctoris Ltd is an Oxford-based research company that is revolutionising drug discovery for biotechnology companies, pharmaceutical corporations and academia. Arctoris has established the world's first fully automated drug discovery platform, offering pre-optimised and fully validated R&D processes for its partners and customers globally. Accessible remotely, the platform provides on-demand access to a wide range of biochemical, cell biology and molecular biology assays conducted by robotics, enabling rapid, informed decision-making in basic biology, target validation, toxicology and phenotypic screening. These assay capabilities are accessed using a powerful online portal that streamlines experiment planning, ordering, tracking and data analysis. Thanks to the Arctoris platform, partners and clients can rapidly, accurately and cost-effectively perform their research and advance their drug discovery programmes.