Tuesday, April 30, 2019

Insilico to present at the FT US Pharma and Biotech Summit

Monday, April 29, 2019 - Insilico Medicine, a biotech company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, will present its latest results in modern and next-generation AI for drug discovery and productive longevity at the Financial Times' US Pharma and Biotech Summit in New York, May 14. 
Artificial intelligence (AI) has the potential to transform the pharmaceutical industry, making the hunt for new pharmaceuticals quicker and more effective. With AI comes the potential to improve drug approval rates, reduce development costs, and help patients comply with their treatments. 
At Insilico, AI has been used as a powerful tool to identify targets for drug development, and with the ability to simulate and accelerate research processes, artificial intelligence helps more drugs to be discovered and come to market quickly. The presentation will focus on the latest advances in artificial intelligence for discovery, development and real world evidence collection of drugs and geroprotectors.
"We are happy to present our latest research at the FT US Pharma and Biotech Summit, which gathers the leading pharma leaders. The AI for Drug Discovery is rapidly gaining popularity, and we are happy to be at the leading edge of this research and one of the innovation drivers in the area," said Alex Zhavoronkov, Ph.D., Founder, and CEO of Insilico Medicine, Inc.
The Financial Times' US Pharma and Biotech Summitwill assemble a distinguished line-up of industry leaders and experts to share insights and perspectives on the critical issues set to re-shape the pharmaceutical sector. 
The event is presented by the Financial Times - one of the world's leading business news organisations, recognised internationally for its authority, integrity and accuracy. The FT has a record paying readership of one million, three-quarters of which are digital subscriptions. It is part of Nikkei Inc., which provides a broad range of information, news and services for the global business community.
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For further information about the event, please contact: 
Alexsandra Silva alexsandra.silva@ft.com
For further information, images or interviews, please contact:
Contact: Klug Gehilfe ai@pharma.ai
Insilico Medicine is regularly publishing research papers in peer-reviewed journals. The company was first to apply the generative adversarial networks (GANs) to the generation of the new molecular structures with the specified parameters and published a seminal peer-reviewed paper submitted in June 2016. The concept was further extended and augmented with advanced memory and reinforcement learning. One of the latest papers published in the Journals of Gerontology demonstrated the application of the deep neural networks to assessing the biological age of the patients. The latest special issue in Molecular Pharmaceutics featured several research papers by Insilico Medicine. Insilico published an overview of its results in aging researchincluding the development of AI aging biomarkers, target identification, cross-species comparison and geroprotector discovery in Aging Research Reviews, one of the highest-impact journals in the field. 
About Insilico Medicine, Inc
Insilico Medicine is an artificial intelligence company headquartered in Rockville, with R&D and management resources in Belgium, Russia, UK, Taiwan, and Korea sourced through hackathons and competitions. The company and its scientists are dedicated to extending human productive longevity and transforming every step of the drug discovery and drug development process through excellence in biomarker discovery, drug development, digital medicine, and aging research.
Insilico pioneered the applications of the generative adversarial networks (GANs) and reinforcement learning for generation of novel molecular structures for the diseases with a known target and with no known targets. In addition to working collaborations with the large pharmaceutical companies, the company is pursuing internal drug discovery programs in cancer, dermatological diseases, fibrosis, Parkinson's Disease, Alzheimer's Disease, ALS, diabetes, sarcopenia, and aging. Through a partnership with LifeExtension.com, the company launched a range of nutraceutical products compounded using the advanced bioinformatics techniques and deep learning approaches. It also provides a range of consumer-facing applications including Young.AI.
In 2017, NVIDIA selected Insilico Medicine as one of the Top 5 AI companies in its potential for social impact. In 2018, the company was named one of the global top 100 AI companies by CB Insights. In 2018 it received the Frost & Sullivan 2018 North American Artificial Intelligence for Aging Research and Drug Development Award accompanied with the industry brief. Brief company video: https://www.youtube.com/watch?v=l62jlwgL3v8.
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Friday, April 26, 2019

Insilico to present at the Pioneers '19

Friday, April 26, 2019 - Insilico Medicine, a biotech company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, will present its latest results in modern and next-generation AI for drug discovery and productive longevity at the Pioneers '19 in Vienna, May 10. 
Artificial intelligence (AI) has the potential to transform the pharmaceutical industry, making the hunt for new pharmaceuticals quicker and more effective. With AI comes the potential to improve drug approval rates, reduce development costs, and help patients comply with their treatments. 
At Insilico, AI has been used as a powerful tool to identify targets for drug development, and with the ability to simulate and accelerate research processes, artificial intelligence helps more drugs to be discovered and come to market quickly. The presentation will focus on the latest advances in artificial intelligence for discovery, development and real world evidence collection of drugs and geroprotectors.
"We look forward to welcoming Alex at our flagship event in Vienna for the second time and hearing more about his pioneering work in the HealthTech field," says Oliver Csendes, Pioneers CEO. "Healthy longevity is a main theme of this year's event, which will take our guests on a technological walk through life, and we're proud to welcome experts like him to support us in going beyond the tech hype."
"We are happy to present our latest research at the Pionners'19, which gathers the leading longevity leaders. The topic of healthy longevity is rapidly gaining popularity, and we are happy to be at the leading edge of this research and one of the innovation drivers in the area," said Alex Zhavoronkov, Ph.D., Founder, and CEO of Insilico Medicine, Inc.
Pioneers '19 is the ultimate meeting point for 2500 bold, pioneering entrepreneurs to look into the future and beyond. A global community of selected startups, executives and investors join forces under the roof of the 500-year-old Hofburg Imperial Palace in Vienna to inspire, empower and create platforms where innovation can thrive and result in profitable new business relationships. Under this year's theme of "Walk the Talks" attendees will get the chance to go beyond the technology hype while remaining firmly rooted in the reality of our future and discovering how deep-tech is redefining our world.
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Insilico Medicine is regularly publishing research papers in peer-reviewed journals. The company was first to apply the generative adversarial networks (GANs) to the generation of the new molecular structures with the specified parameters and published a seminal peer-reviewed paper submitted in June 2016. The concept was further extended and augmented with advanced memory and reinforcement learning. One of the latest papers published in the Journals of Gerontologydemonstrated the application of the deep neural networks to assessing the biological age of the patients. The latest special issue in Molecular Pharmaceutics featured several research papers by Insilico Medicine. Insilico published an overview of its results in aging research including the development of AI aging biomarkers, target identification, cross-species comparison and geroprotector discovery in Aging Research Reviews, one of the highest-impact journals in the field.
In 2017, NVIDIA selected Insilico Medicine as one of the Top 5 AI companies in its potential for social impact. In 2018, the company was named one of the global top 100 AI companies by CB Insights. In 2018 it received the Frost & Sullivan 2018 North American Artificial Intelligence for Aging Research and Drug Development Award accompanied with the industry brief. Brief company video: https://www.youtube.com/watch?v=l62jlwgL3v8.
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Wednesday, April 24, 2019

Insilico to present at the Health Horizons Future Healthcare Forum

Tuesday, April 23, 2019 - Insilico Medicine, a biotech company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, will present its latest results in modern and next-generation AI for drug discovery and productive longevity at the Health Horizons Future Healthcare Forum in London, June 26. 
Artificial intelligence (AI) has the potential to transform the pharmaceutical industry, making the hunt for new pharmaceuticals quicker and more effective. With AI comes the potential to improve drug approval rates, reduce development costs, and help patients comply with their treatments. 
At Insilico, AI has been used as a powerful tool to identify targets for drug development, and with the ability to simulate and accelerate research processes, artificial intelligence helps more drugs to be discovered and come to market quickly. The presentation will focus on the latest advances in artificial intelligence for discovery, development and real world evidence collection of drugs and geroprotectors.
"The healthcare industry is just at the beginning of a revolutionary transformation and we aim to shape not just the debate, but also tangible government, industry and academic initiatives to create more innovative, but also more affordable and accessible, future healthcare that not only treats but also prevents disease," said Dr. Marek Tyl, CEO of the Innovation Forum.
"Artificial Intelligence in Healthcare has long been a concept carrying tremendous promise, with seemingly limitless potential to increase industry efficiency and improve lives on a global scale. Within biotech, AI has enabled identification of new disease mechanisms, pathways, targets and drugs to better match patients to appropriate therapies and deliver on the ideals of precision medicine. The advancements we have already achieved and the discovery work being presented by Insilico and others at the Health Horizons Future Healthcare Forum excites us about the future of healthcare," said Annastasiah Mudiwa Mhaka, Ph.D., president of the Alliance for Artificial Intelligence in Healthcare (AAIH).
"We are happy to present our latest research at the Health Horizons Future Healthcare Forum, which gathers the leading longevity leaders. The topic of machine learning implementation in drug discovery is rapidly gaining popularity, and we are happy to be at the leading edge of this research and one of the innovation drivers in the area," said Alex Zhavoronkov, Ph.D., Founder, and CEO of Insilico Medicine, Inc.
Health Horizons is a high calibre, two-day conference focusing on the future of the healthcare industry. The Forum aims to deliver 1,500 attendees, more than 100 speakers, healthcare leaders and investors, to discuss the most pertinent challenges to the health ecosystems. Health Horizons is a unique conference focusing on the future of health and healthcare, which gives delegates an interdisciplinary view of the health innovation landscape. The key themes that Health Horizons aims to approach include: novel therapeutic approaches, digital health, AI and data in healthcare, cardiometabolic disease, longevity, new models for funding healthcare innovation, nanotechnology and sensing in healthcare, delivering affordable innovative medicines to patients, breakthroughs against the incurables, future of oncology and rare diseases. 
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For further information, images or interviews, please contact:
Contact: Klug Gehilfe
Insilico Medicine is regularly publishing research papers in peer-reviewed journals. The company was first to apply the generative adversarial networks (GANs) to the generation of the new molecular structures with the specified parameters and published a seminal peer-reviewed paper submitted in June 2016. The concept was further extended and augmented with advanced memory and reinforcement learning. One of the latest papers published in the Journals of Gerontologydemonstrated the application of the deep neural networks to assessing the biological age of the patients. The latest special issue in Molecular Pharmaceutics featured several research papers by Insilico Medicine. Insilico published an overview of its results in aging research including the development of AI aging biomarkers, target identification, cross-species comparison and geroprotector discovery in Aging Research Reviews, one of the highest-impact journals in the field.
In 2017, NVIDIA selected Insilico Medicine as one of the Top 5 AI companies in its potential for social impact. In 2018, the company was named one of the global top 100 AI companies by CB Insights. In 2018 it received the Frost & Sullivan 2018 North American Artificial Intelligence for Aging Research and Drug Development Award accompanied with the industry brief. Brief company video: https://www.youtube.com/watch?v=l62jlwgL3v8.
About Insilico Medicine, Inc
Insilico Medicine is an artificial intelligence company headquartered in Rockville, with R&D and management resources in Belgium, Russia, UK, Taiwan, and Korea sourced through hackathons and competitions. The company and its scientists are dedicated to extending human productive longevity and transforming every step of the drug discovery and drug development process through excellence in biomarker discovery, drug development, digital medicine, and aging research.
Insilico pioneered the applications of the generative adversarial networks (GANs) and reinforcement learning for generation of novel molecular structures for the diseases with a known target and with no known targets. In addition to working collaborations with the large pharmaceutical companies, the company is pursuing internal drug discovery programs in cancer, dermatological diseases, fibrosis, Parkinson's Disease, Alzheimer's Disease, ALS, diabetes, sarcopenia, and aging. Through a partnership with LifeExtension.com, the company launched a range of nutraceutical products compounded using the advanced bioinformatics techniques and deep learning approaches. It also provides a range of consumer-facing applications including Young.AI.

In 2017, NVIDIA selected Insilico Medicine as one of the Top 5 AI companies in its potential for social impact. In 2018, the company was named one of the global top 100 AI companies by CB Insights. In 2018 it received the Frost & Sullivan 2018 North American Artificial Intelligence for Aging Research and Drug Development Award accompanied with the industry brief. Brief company video: https://www.youtube.com/watch?v=l62jlwgL3v8.
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Thursday, April 18, 2019

Scientists enter research collaboration to outsmart cancer

Wednesday, April 17, 2019 - Cancer is a disease that afflicts an alarming number of people, with one in two being diagnosed with a type of cancer during their lifetime. The global cancer burden has risen to 18.1 million people in 2018, which makes cancer one of the leading causes of death worldwide. While clinical developments and advances in early detection and treatment have already changed the lives of many people suffering from this disease, there is still a tremendous need to develop new knowledge and make new breakthroughs in cancer drug discovery and development. 
Effective cancer research is unthinkable without collaboration. The field is immense and new developments are occurring all the time, so partnerships are key - whether internal, external or interdisciplinary. 
Today, Insilico Medicine, a biotech company developing the end-to-end drug discovery pipeline utilizing next-generation artificial intelligence, announces its partnership with Arctoris, the world's first fully automated cancer research laboratory providing robotic experimentation in the cloud, Science Entrepreneur Club, a life sciences network and Cluster Market, a leading online equipment sharing and booking platform enabling and accelerating science. 
The goal of this collaboration is to conduct BioTarget, which is dedicated to finding new molecules for cancer treatments from collaborating partners worldwide, and to raising awareness for entrepreneurship and innovation amongst scientists. We also aspire to unite the life science ecosystem by educating, inspiring biotech companies to form powerful connections and receive grants for experiments. The initiative is supported by Cancer Research UK, the world's largest independent cancer research charity organisation. 
"Our mission is to enable the brightest minds worldwide to tackle one of the hardest problems, cancer, by putting cutting-edge research capabilities at scientists' fingertips. BioTarget is a unique way to identify and bring together the next generation of cancer biotech companies, and we are proud to be a founding partner of this unique collaborative effort," said Martin-Immanuel Bittner, Co-Founder & Director of Arctoris.
"This collaboration was established for a single purpose: to support combined efforts to find a cure for and eliminate cancer. By using our resources and working with others dedicated to a common cause, there is a hope that together we can beat this disease," said Alex Zhavoronkov, Ph.D., Founder, and CEO of Insilico Medicine, Inc.
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About BioTarget 2019
BioTarget is the world's first biotech competition for emerging companies dedicated to finding new molecules for cancer treatment. BioTarget also aims to raise awareness for entrepreneurship and innovation amongst scientists in academia and industry alike. It allows companies to showcase their innovation to a great audience, meet leading biotech investors and industry professionals that can help them reach the next milestone towards developing new drugs for cancer patients..
Official Website: https://www.biotarget.org/
For further information, images or interviews, please contact:
Insilico Medicine Contact: Klug Gehilfe ai@pharma.ai
Official Website: http://insilico.com/
About Insilico Medicine, Inc
Insilico Medicine is an artificial intelligence company headquartered in Rockville, with R&D and management resources in Belgium, Russia, UK, Taiwan, and Korea sourced through hackathons and competitions. The company and its scientists are dedicated to extending human productive longevity and transforming every step of the drug discovery and drug development process through excellence in biomarker discovery, drug development, digital medicine, and aging research.
Insilico pioneered the applications of the generative adversarial networks (GANs) and reinforcement learning for generation of novel molecular structures for the diseases with a known target and with no known targets. In addition to working collaborations with the large pharmaceutical companies, the company is pursuing internal drug discovery programs in cancer, dermatological diseases, fibrosis, Parkinson's Disease, Alzheimer's Disease, ALS, diabetes, sarcopenia, and aging. Through a partnership with LifeExtension.com, the company launched a range of nutraceutical products compounded using the advanced bioinformatics techniques and deep learning approaches. It also provides a range of consumer-facing applications including Young.AI.
In 2017, NVIDIA selected Insilico Medicine as one of the Top 5 AI companies in its potential for social impact. In 2018, the company was named one of the global top 100 AI companies by CB Insights. In 2018 it received the Frost & Sullivan 2018 North American Artificial Intelligence for Aging Research and Drug Development Award accompanied with the industry brief. Brief company video: https://www.youtube.com/watch?v=l62jlwgL3v8
Arctoris Contact: Martin-Immanuel Bittner martin-immanuel.bittner@arctoris.com
About Arctoris
Based in Oxford, UK, Arctoris is the world's first fully automated cloud lab for cancer research, enabling academic scientists worldwide to directly configure a wide range of cancer research experiments online, and have them completed at its robotic facility. Arctoris offers its clients and partners a wide range of techniques to cover cellular and molecular biology, providing a platform solution from experiment design via robotic experimentation to data storage and visualisation.
Arctoris is actively partnering with academic centres and drug discovery companies to move their drug candidates forward, leveraging its robotic platform to generate data of unprecedented quality and depth. 
Official Website: https://arctoris.com/
About Cancer Research UK 
Cancer Research UK is the world's largest independent cancer research charity that conducts research into the prevention, diagnosis and treatment of the disease. Research activities are carried out in institutes, universities and hospitals across the UK, both by the charity's own employees and by its grant-funded researchers. It also provides information about cancer and runs campaigns aimed at raising awareness of the disease and influencing public policy. Cancer Research UK's work is almost entirely funded by the public. It raises money through donations, legacies, community fundraising, events, retail and corporate partnerships. Over 40,000 people are regular volunteers.
About Science Entrepreneur Club 
The Science Entrepreneur Club aims to boost innovation by uniting the key stakeholders in the life science industry. The SEC provides (early stage) scientific entrepreneurs with a revolutionary network and platform to showcase their innovative technologies, accelerate their company and find investors. Their events provide you with a unique opportunity to blend with the most innovative entrepreneurs and give you an insight into the hidden world of startups. 
About Cluster Market
Cluster Market is building a world leading online equipment sharing and booking platform enabling and accelerating science. Clustermarket's marketplace is giving scientists easy and affordable access to equipment and technical services in nearby institutions. Research facilities/labs have the opportunity to promote their resources to external businesses, colleagues or even international collaboration partners.
Official Website: https://www.clustermarket.com/
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Tuesday, April 16, 2019

PetSensus and Insilico Medicine partner on animal health data to extend pet longevity

Tuesday, April 16, 2019 - Animal biomedical data start-up PetSensus and  Insilico Medicine, a company specializing in the application of deep learning for target identification and drug discovery in humans, announce a collaboration in animal longevity.
Around the world pets are often considered members of the family and there is an increasing awareness of their health and wellbeing which has many economic and emotional benefits. More than 95% of Americans view their pets as family, and spend increasing amounts of money on personalized nutrition and care. At the same time, pet health indicators such as the incidence of obesity, diabetes and dental disease are at historic highs, affecting eight in every ten cats and dogs. In fact, cancer is a leading cause of death among dogs, even though it is treatable in half of all cases if diagnosed early on.
Unfortunately, due to the high costs of drug development and absence of reimbursement mechanisms, drug discovery research in animals intended to extend healthy productive longevity is stalling. 
In order to accelerate the development of innovative interventions in the aging of pets and service animals using the latest advances in artificial intelligence, a large amount of multi-modal animal health data will be required. PetSensus seeks to address this issue with its biomedical data platform. 
Big data analytics can generate predictive insights quicker, cheaper and more accurately than the millions of animal tests conducted each year. AI holds the key to radically reducing the amount of animal testing taking place, while simultaneously returning far greater benefit to human health.
"Innovative companies such as Insilico Medicine leverage the power of AI to achieve what the pharma industry takes years, thousands of employees and millions of dollars to achieve. We want to bring the same capabilities to animal health," said Martin Razuks-Ebels, founder and CEO of PetSensus. 
While Insilico Medicine's impressive list of partners already spans several Big Pharma, biotechnology and academic partnerships, the partnership with PetSensus will unlock new possibilities in animal health. 
"Not only can our experience from the human industry be translated to the animal space, but the new findings from the animal industry will likewise be applicable in areas of human health. Humans and dogs share around 82% of the same genes, while that number is as high as 90% for cats, which entails a lot of potential overlap in illnesses," said Alex Zhavoronkov, founder and CEO of Insilico Medicine. 
"At Insilico Medicine we do not use identifiable data from patients and instead rely on publicly available data to identify disease targets and generate small molecules to eliminate the possibility of data breach. While still requiring oversight, animal data can be used and shared more freely and without the risk of infringing someone's privacy. We are happy to partner with PetSensus, one of the first companies to focus on animal data markets," added Alex Zhavoronkov, CEO of Insilico Medicine
"While it is old news that pet owners live happier and healthier lives, PetSensus will empower pet owners to step up to the task and play a central role in improving their pets' as well as their own well-being in the long-term," said Razuks-Ebels, CEO of Petsensus.
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For further information, images or interviews, please contact:
Contact: Maryna Petrychenko 
mp@petsensus.com
About Insilico Medicine, Inc
Insilico Medicine, Inc. is an artificial intelligence company with R&D and management resources in Belgium, Russia, UK, Taiwan and Korea. The company and its scientists are dedicated to extending human productive longevity and transforming every step of the drug discovery and drug development process through excellence in biomarker discovery, drug development, digital medicine and aging research. 
Insilico pioneered the applications of generative adversarial networks (GANs) and reinforcement learning for generation of novel molecular structures for diseases with a known target as well as those with no known targets. In addition to collaborations with large pharmaceutical companies, the company is pursuing internal drug discovery programs in cancer, dermatological diseases, fibrosis, Parkinson's Disease, Alzheimer's Disease, ALS, diabetes, sarcopenia, and aging. 
For more information visit: http://www.insilico.com
About PetSensus
PetSensus is a Latvia-based animal biomedical data start-up that unites pet owners and pet care companies to improve pet wellness and longevity. 
The blockchain-connected platform uses deep veterinary knowledge and AI tools to generate personalized pet care insights on the basis of each pet's unique biomedical data. Research organizations, on the other hand, obtain access to this live population dataset, trial target recruitment tools, and on-demand cutting-edge analytics tools to enable a new era of research and development in pet wellness that rivals human healthcare.
For more information visit: http://www.petsensus.com
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Tuesday, April 9, 2019

David Gems to present at the 6th Aging Research for Drug Discovery Forum in Basel

Tuesday, April 9, 2019 - Today Insilico Medicine, a biotechnology company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, and the Scheibye-Knudsen Lab, University of Copenhagen, announce the presentation of David Gems, Ph.D., Professor of Biogerontology at the Institute of Healthy Ageing, University College London, at the 6th Aging Research, Drug Discovery, and AI Forum during the Basel Life Congress, September 10-12, 2019, Basel, Switzerland.
David Gems will give a talk titled "New discoveries about ageing in C. elegans" presenting the mechanisms by which senescent pathologies originate in these nematode worms, providing clues to understanding the nature of senescent pathologies in humans.
Studies of the genetics of ageing in C. elegans have yielded riches in terms of new genes and pathways affecting lifespan, but the proximate mechanisms of ageing that such genes influence remain uncertain. Recent work in Dr. Gems lab is testing hypotheses based on ideas from George Williams and Misha Blagosklonny where senescent pathologies that limit lifespan are driven primarily by late-life, futile run-on of wild-type biological programs, rather than damage accumulation. They motivate a new, pathology-centred approach to understanding senescence, particularly via the study of how pathologies develop, and how they cause mortality. 
"The nature of the primary causes of ageing is perhaps the most important unsolved puzzle in biomedical research," said David Gems, Ph.D., Professor of Biogerontology at the Institute of Healthy Ageing, University College London.
"I am really excited that professor David Gems from University College London has decided to join our meeting. Professor Gems is a leading figure in biogerontology and has been spearheading our understanding of aging using the C. elegans model organism. Through his career, he has remained a voice of reason fearlessly questioning emerging hypotheses and supplying new evidence in our understanding of how aging may be regulated. I am therefore very happy that he has chosen to join our meeting and I very much look forward to his undoubtedly fascinating talk." said Morten Scheibye-Knudsen, MD, Ph.D., University of Copenhagen.
"Over the last 5 years, the "Aging & Drug Discovery" and "AI for Healthcare" forums have been leading events at BaselLife, attracting hundreds of delegates from over 50 countries. This year, we are combining the 2 platforms into a 3 day-event titled "the 6th Aging, AI and Drug Discovery Forum" to explore the convergence of these 2 cutting edge disciplines. Under the program leadership of Professor Morten Scheibye-Knudsen and Dr. Alex Zhavoronkov, with distinguished scientists and industry experts in the field, we look forward to exploring breakthroughs for this great healthcare need for the planet," said Dr. Bhupinder Bhullar, Chair, Innovation Forum program committee, Basel Life 2019. 
"The 6th annual Aging Research, Drug Discovery, and AI Forum at Basel Life will have a fresh program featuring some of the most prominent scientists and industry players in aging and longevity research covering the theory, applications and convergence of these three exciting areas," said Alex Zhavoronkov, Ph.D., Founder, and CEO of Insilico Medicine, Inc.
The 6th Aging Research for Drug Discovery Forum Basel will bring together leaders in the aging, longevity, and drug discovery field, to describe the latest progress in the molecular, cellular and organismal basis of aging and the search for interventions. Furthermore, the forum will include opinion leaders in AI to discuss the latest advances of this technology in the biopharmaceutical sector and how this can be applied to interventions. This event intends to bridge academic and commercial research and foster collaborations that will result in practical solutions to one of humanity's most challenging problems: aging. The Forum will be held in Basel, Switzerland, September 10-12, 2019. 
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Insilico Medicine Contact: Ola Popova
About Insilico Medicine, Inc
Insilico Medicine is an artificial intelligence company headquartered in Rockville, with R&D and management resources in Belgium, Russia, UK, Taiwan, and Korea sourced through hackathons and competitions. The company and its scientists are dedicated to extending human productive longevity and transforming every step of the drug discovery and drug development process through excellence in biomarker discovery, drug development, digital medicine, and aging research.
Insilico pioneered the applications of the generative adversarial networks (GANs) and reinforcement learning for generation of novel molecular structures for the diseases with a known target and with no known targets. In addition to working collaborations with the large pharmaceutical companies, the company is pursuing internal drug discovery programs in cancer, dermatological diseases, fibrosis, Parkinson's Disease, Alzheimer's Disease, ALS, diabetes, sarcopenia, and aging. Through a partnership with LifeExtension.com, the company launched a range of nutraceutical products compounded using the advanced bioinformatics techniques and deep learning approaches. It also provides a range of consumer-facing applications including Young.AI.
In 2017, NVIDIA selected Insilico Medicine as one of the Top 5 AI companies in its potential for social impact. In 2018, the company was named one of the global top 100 AI companies by CB Insights. In 2018 it received the Frost & Sullivan 2018 North American Artificial Intelligence for Aging Research and Drug Development Award accompanied with the industry brief. Brief company video: https://www.youtube.com/watch?v=l62jlwgL3v8.
About David Gems 
David Gems is Professor of Biogerontology at the UCL Institute of Healthy Ageing, of which he is a founder member and a director. He has a B.Sc. in Biochemistry from Sussex University, and a Ph.D. in Genetics from Glasgow University. He was a postdoc at Imperial College, and the University of Missouri-Columbia, USA before founding his own research group at UCL in 1997 as a Royal Society University Research Fellow. The aims of his research are to understand the causes of ageing, and identify general principles of pathophysiology for late-life diseases. Much of his work uses the nematode worm C. elegans, but he has also contributed to studies of aging in other nematodes, Drosophila and the mouse, and penned articles on ageing and ethics. Ageing is now the main cause of serious illness worldwide, yet its underlying biology remains poorly understood. Understanding ageing is key to treating late-life disease.
About UCL
University College London is a public research university located in London, United Kingdom. It is a constituent college of the federal University of London, and is the third largest university in the United Kingdom by total enrolment, and the largest by postgraduate enrolment.
Established in 1826 as London University by founders inspired by the radical ideas of Jeremy Bentham, UCL was the first university institution to be established in London, and the first in England to be entirely secular and to admit students regardless of their religion. In 1836 UCL became one of the two founding colleges of the University of London, which was granted a royal charter in the same year. It has grown through mergers, including with the Institute of Neurology (in 1997), the Royal Free Hospital Medical School (in 1998), the Eastman Dental Institute (in 1999), the School of Slavonic and East European Studies (in 1999), the School of Pharmacy (in 2012) and the Institute of Education (in 2014)
Official Website: https://www.ucl.ac.uk/
About the Scheibye-Knudsen Laboratory
The growing proportion of the elderly population represents an increasing socioeconomic challenge, not least because of age-associated diseases. It is therefore increasingly pertinent to find interventions for age-associated diseases such as Alzheimer's, Parkinson's and cardiovascular diseases. Although the cause of aging is currently unknown accumulation of damage to our genome, the DNA, may be a contributing factor.
In the Scheibye-Knudsen lab we try to understand the cellular and organismal consequences of DNA damage with the aim of developing interventions. We have discovered that DNA damage leads to changes in certain metabolites and that replenishment of these molecules may alter the rate of aging in model organisms. These findings suggest that normal aging and age-associated diseases may be malleable to similar interventions. The hope is to develop interventions that will allow everyone to live healthier, happier and more productive lives.
Laboratory website: http://scheibye-knudsen.com/
About the University of Copenhagen
With over 40,000 students and more than 9,000 employees, the University of Copenhagen is the largest institution of research and education in Denmark and among the highest ranked universities in Europe. The purpose of the University - to quote the University Statute - is to 'conduct research and provide further education to the highest academic level'. Approximately one hundred different institutes, departments, laboratories, centres, museums, etc., form the nucleus of the University.
About Basel Life 2019
Aging Research for Drug Discovery Forum description 
In this symposium, leaders in the aging, longevity, and drug discovery field will describe the latest progress in the molecular, cellular and organismal basis of aging and the search for interventions. Furthermore, the forum will include opinion leaders in AI to discuss the latest advances of this technology in the biopharmaceutical sector and how this can be applied to interventions. This event intends to bridge academic and commercial research and foster collaborations that will result in practical solutions to one of humanity's most challenging problems: aging. A panel of thought-leaders will give us their cutting edge reports on the latest progress in our quest to extend the healthy lifespan of everyone on the planet. 
Conference Official Website: https://www.basellife.org/2019.html

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Monday, April 8, 2019

Insilico to present at the 3rd Annual MAQC Society Conference

 Insilico Medicine, a biotechnology company developing the end-to-end drug discovery pipeline utilizing the next generation artificial intelligence, will present its latest results in modern and next-generation AI for Drug Discovery at the 3rd Annual MAQC Conference in Italy, April 8-10. 
Deep Learning methods have proven to be an effective tool to optimize key steps of the drug discovery pipeline, such as target identification and design of molecular compounds with desired properties. However, the systematic application of DL within these fields and for high-stakes decisions in healthcare drives specific demands for better interpretability and reproducibility. 
While the specificity of DL architectures and learning processes require adapted solutions, researches are currently undertaken to design computational methods and workflows which can be used to make these types of approaches more interpretable and guarantee that results are reproducible.
The presentation will focus on the aspects that make achieving reproducibility challenging, ways of resolving potential issues, as well as recent developments that aim at making DL models more interpretable.
"We are happy to present our latest research at the 3rd Annual MAQC Conference, which gathers the key longevity leaders. The topic of AI for Drug Discovery and Productive longevity is rapidly gaining popularity, and we are happy to be at the leading edge of this research and one of the innovation drivers in the area," said Quentin Vanhaelen, Ph.D., Director, Virtual Human Project at Insilico Medicine.
The focus of the MAQC 2019 meeting is the challenge of applying Artificial Intelligence and Machine Learning to biological, health, and medical problems, still adopting reproducible science principles for a medicine safely based on the trustworth and fair analysis of massive data. The event is held in Riva del Garda, Italy, on April 8-10, 2019. 
Insilico Medicine is regularly publishing research papers in peer-reviewed journals. The company was first to apply the generative adversarial networks (GANs) to the generation of the new molecular structures with the specified parameters and published a seminal peer-reviewed paper submitted in June 2016. The concept was further extended and augmented with advanced memory and reinforcement learning. One of the latest papers published in the Journals of Gerontologydemonstrated the application of the deep neural networks to assessing the biological age of the patients. The latest special issue in Molecular Pharmaceutics featured several research papers by Insilico Medicine. Insilico published an overview of its results in aging research including the development of AI aging biomarkers, target identification, cross-species comparison and geroprotector discovery in Aging Research Reviews, one of the highest-impact journals in the field. 
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For further information, images or interviews, please contact:
Contact: Klug Gehilfe 
ai@pharma.ai 
Website: http://insilico.com/ 
Official website of the conference: https://maqc2019.fbk.eu/
About Insilico Medicine, Inc
Insilico Medicine is an artificial intelligence company headquartered in Rockville, with R&D and management resources in Belgium, Russia, UK, Taiwan, and Korea sourced through hackathons and competitions. The company and its scientists are dedicated to extending human productive longevity and transforming every step of the drug discovery and drug development process through excellence in biomarker discovery, drug development, digital medicine, and aging research.
Insilico pioneered the applications of the generative adversarial networks (GANs) and reinforcement learning for generation of novel molecular structures for the diseases with a known target and with no known targets. In addition to working collaborations with the large pharmaceutical companies, the company is pursuing internal drug discovery programs in cancer, dermatological diseases, fibrosis, Parkinson's Disease, Alzheimer's Disease, ALS, diabetes, sarcopenia, and aging. Through a partnership with LifeExtension.com, the company launched a range of nutraceutical products compounded using the advanced bioinformatics techniques and deep learning approaches. It also provides a range of consumer-facing applications including Young.AI.
In 2017, NVIDIA selected Insilico Medicine as one of the Top 5 AI companies in its potential for social impact. In 2018, the company was named one of the global top 100 AI companies by CB Insights. In 2018 it received the Frost & Sullivan 2018 North American Artificial Intelligence for Aging Research and Drug Development Award accompanied with the industry brief. Brief company video: https://www.youtube.com/watch?v=l62jlwgL3v8. 

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